Article
Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.
Nature genetics - 1 Feb 2010
Crowther-Swanepoel Dalemari, Broderick Peter, Di Bernardo Maria Chiara, Dobbins Sara E, Torres María, Mansouri Mahmoud, Ruiz-Ponte Clara, Enjuanes Anna, Rosenquist Richard, Carracedo Angel, Jurlander Jesper, Campo Elias, Juliusson Gunnar, Montserrat Emilio, Smedby Karin E, Dyer Martin J S, Matutes Estella, Dearden Claire, Sunter Nicola J, Hall Andrew G, Mainou-Fowler Tryfonia, Jackson Graham H, Summerfield Geoffrey, Harris Robert J, Pettitt Andrew R, Allsup David J, Bailey James R, Pratt Guy, Pepper Chris, Fegan Chris, Parker Anton, Oscier David, Allan James M, Catovsky Daniel, Houlston Richard S
Abstract excerpt
To identify new risk variants for chronic lymphocytic leukemia (CLL), we conducted a genome-wide association study of 299,983 tagging SNPs, with validation in four additional series totaling 2,503 cases and 5,789 controls. We identified four new risk loci for CLL at 2q37.3 (rs757978, FARP2; odds...
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