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Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia: a CRuCIAL study

17 May 2022

Abstract excerpt

During the past years, considerable efforts have been made to uncover the genetic component of chronic lymphocytic leukemia (CLL) susceptibility. To date, several genome-wide association studies (GWAS) and their meta-analysis have identified not only single-nucleotide polymorphisms (SNPs) associated with CLL risk [ 1 ] but also patient survival [ 2 ]. However, despite these noticeable results, it becomes evident...

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PMID: 35581176
DOI: 10.1038/s41408-022-00676-8

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