A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.

doi:10.1038/ng.2843

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Article

A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.

Nature genetics - 1 Jan 2014

Speedy Helen E, Di Bernardo Maria Chiara, Sava Georgina P, Dyer Martin J S, Holroyd Amy, Wang Yufei, Sunter Nicola J, Mansouri Larry, Juliusson Gunnar, Smedby Karin E, Roos Göran, Jayne Sandrine, Majid Aneela, Dearden Claire, Hall Andrew G, Mainou-Fowler Tryfonia, Jackson Graham H, Summerfield Geoffrey, Harris Robert J, Pettitt Andrew R, Allsup David J, Bailey James R, Pratt Guy, Pepper Chris, Fegan Chris, Rosenquist Richard, Catovsky Daniel, Allan James M, Houlston Richard S

Abstract excerpt

Genome-wide association studies (GWAS) of chronic lymphocytic leukemia (CLL) have shown that common genetic variation contributes to the heritable risk of CLL. To identify additional CLL susceptibility loci, we conducted a GWAS and performed a meta-analysis with a published GWAS totaling 1,739 individuals with CLL (cases) and 5,199 controls with validation in an additional 1,144 cases and 3,151 controls. A...

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PMID: 24292274
DOI: 10.1038/ng.2843

Genes

IPCEF1
POT1
TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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