Article
Molecular basis of organ-specific selection of viral variants during chronic infection.
Journal of virology - 1 Aug 1991
Ahmed R, Hahn C S, Somasundaram T, Villarete L, Matloubian M, Strauss J H
Abstract excerpt
Viral variants of different phenotypes are present in the central nervous system (CNS) and lymphoid tissues of carrier mice infected at birth with the Armstrong strain of lymphocytic choriomeningitis virus. The CNS isolates are similar to the parental virus and cause acute infections in adult mic...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Brain
- Carrier State
- Chronic Disease
- Gene Frequency
- Glycoproteins
- Leucine
- Lymphocytic Choriomeningitis
- Lymphocytic choriomeningitis virus
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutation
- Oligonucleotides
- Organ Specificity
- Phenylalanine