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Article

Host range determinants located on the interior of the poliovirus capsid.

The EMBO journal - 1 May 1991

Moss E G, Racaniello V R

Abstract excerpt

The inability of certain poliovirus strains to infect mice can be overcome by the expression of human poliovirus receptors in mice or by the presence of a particular amino acid sequence of the B-C loop of the viral capsid protein VP1. We have identified changes in an additional capsid structure that permit host-restricted poliovirus strains to infect mice. Variants of the mouse-virulent P2/Lansing strain were...

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Identifiers

PMID: 1850692
DOI: 10.1002/j.1460-2075.1991.tb08046.x
PMCID: PMC452759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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