Tissue-mediated selection of viral variants: correlation between glycoprotein mutation and growth in neuronal cells.

Abstract excerpt

Viral variants with different biological properties predominate in the central nervous system (CNS) and lymphoid tissues of carrier mice infected at birth with the Armstrong strain of lymphocytic choriomeningitis virus. The CNS isolates have the same phenotype as the parental strain and cause acu...

Topics

• Animals
• Base Sequence
• Glycoproteins
• Glycosylation
• Lymphocytic choriomeningitis virus
• Mice
• Mice, Inbred BALB C
• Molecular Sequence Data
• Mutation
• Neurons
• Oligonucleotide Probes
• Organ Specificity