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Article

Cyclooxygenase 2 1195G > A polymorphism is associated with chronic obstructive pulmonary disease in Japanese and Chinese patients.

Chinese medical journal - 1 Jun 2013

Chen Li-Jun, Xu Wang, Taooka Yasuyuki, Ohe Miki, Takahashi Hitoshi, Sutani Akihisa, Kuraki Takashige, Isobe Takeshi

Abstract excerpt

BACKGROUND: Cyclooxygenase-2 (COX-2) is overexpressed during airway inflammation in chronic obstructive pulmonary disease (COPD) patients. Single nucleotide polymorphisms (SNPs) in the COX-2 promoter might contribute to differential COX-2 expression and subsequent interindividual variability in susceptibility to COPD. We investigated the association between COX-2 (-765G > C, -1195G > A) polymorphisms and COPD...

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PMID: 23786928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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