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Article

Matrix metalloproteinase-9 -1562C/T promoter polymorphism confers risk for COPD: a meta-analysis.

PloS one - 1 Jan 2013

Chen Lei, Wang Tao, Liu Lian, Shen Yongchun, Wan Chun, Wen Fuqiang

Abstract excerpt

BACKGROUND: The role of matrix metalloproteinase (MMP) gene polymorphisms in the development of chronic obstructive pulmonary disease (COPD) has been reported with inconsistent results. This meta-analysis was performed to assess the association of MMP-1 -1607G/GG and MMP-9 -1562C/T promoter polymorphisms with COPD susceptibility. METHODS: Published case-control studies from Pubmed and China National Knowledge...

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Case-Control Studies
Matrix Metalloproteinase 9
Odds Ratio
Polymorphism, Single Nucleotide
Pulmonary Disease, Chronic Obstructive

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PMID: 23555986
DOI: 10.1371/journal.pone.0060523
PMCID: PMC3610819

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