Article
Association between SNPs in pre-miRNA and risk of chronic obstructive pulmonary disease.
Clinical biochemistry - 1 Jul 2011
Li Li-Juan, Gao Lin-Bo, Lv Mei-Li, Dong Wei, Su Xiao-Wei, Liang Wei-Bo, Zhang Lin
Abstract excerpt
OBJECTIVES: Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airway obstruction and persistent chronic airway inflammation and is influenced by genetic and environmental factors. This study aimed to explore the genetic aspect of its initial occurrence. DESIGN AND METHODS: We conducted a case-control study of 432 COPD patients and 511 control subjects frequency-matched in age and...
Topics
- Aged
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Male
- MicroRNAs
- Polymorphism, Single Nucleotide
- Pulmonary Disease, Chronic Obstructive
