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Article

Cyclooxygenase-2 -765G>C polymorphism is associated with C-reactive protein levels in resistant smokers but not in chronic obstructive pulmonary disease patients.

Respiratory physiology & neurobiology - 15 Jan 2012

López-Campos José Luis, Montes-Worboys Ana, Calero Carmen, Márquez-Martin Eduardo, Cejudo Pilar, Ortega Francisco, Arellano Elena

Abstract excerpt

We sought to investigate whether the serum concentrations of several inflammatory biomarkers are related to the cyclooxygenase-2 (COX2) -765G>C polymorphism in chronic obstructive pulmonary disease (COPD) and a control group of non-COPD smokers. Serum inflammatory markers (CRP, SAA, CXCL8, and sICAM-1) were measured by ELISA in 144 patients with COPD and in 55 control subjects. Genomic DNA was extracted from...

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Identifiers

PMID: 22100366
DOI: 10.1016/j.resp.2011.11.001

Genes

CRP
CXCL8

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