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Article

Assessment of mitotic spindle phenotypes in Drosophila S2 cells.

Methods in cell biology - 1 Jan 2010

Goshima Gohta

Abstract excerpt

The Drosophila S2 cell line is popularly used to study mitosis. In this cell line, multiple genes can be easily and efficiently knocked down by RNA interference (RNAi), and the associated mitotic phenotypes can be assessed with high-resolution microscopy after immunofluorescence or in a living cell. However, compared to untransformed cells in wild-type organisms such as yeasts or worms, mitosis in the S2 cell...

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PMID: 20719276
DOI: 10.1016/S0091-679X(10)97015-5

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