Article
A genetic interaction map of cell cycle regulators.
Molecular biology of the cell - 15 Apr 2016
Billmann Maximilian, Horn Thomas, Fischer Bernd, Sandmann Thomas, Huber Wolfgang, Boutros Michael
Abstract excerpt
Cell-based RNA interference (RNAi) is a powerful approach to screen for modulators of many cellular processes. However, resulting candidate gene lists from cell-based assays comprise diverse effectors, both direct and indirect, and further dissecting their functions can be challenging. Here we screened a genome-wide RNAi library for modulators of mitosis and cytokinesis inDrosophilaS2 cells. The screen identified...
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