Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth.

Nature cell biology - 1 Sept 2008

Wanzel Michael, Russ Annika C, Kleine-Kohlbrecher Daniela, Colombo Emanuela, Pelicci Pier-Guiseppe, Eilers Martin

Abstract excerpt

The Myc-associated zinc-finger protein, Miz1, is a negative regulator of cell proliferation and induces expression of the cell-cycle inhibitors p15(Ink4b) and p21(Cip1). Here we identify the ribosomal protein L23 as a negative regulator of Miz1-dependent transactivation. L23 exerts this function...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Proliferation
Share to Feedback, Physiological
Share to HeLa Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutant Proteins

Share to Nuclear Proteins

Share to Nucleophosmin

Share to Proto-Oncogene Proteins c-myc

Share to Ribosomal Proteins

Source

Identifiers

PMID: 19160485
DOI: 10.1038/ncb1764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19160485-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth.PMID 19160485Read ↗

NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin RemodelingSemantic proximity Read ↗

B23 and ARF: friends or foes?Semantic proximity Read ↗

Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome.Semantic proximity Read ↗

SPIN1 promotes tumorigenesis by blocking the uL18-MDM2-p53 pathwaySemantic proximity Read ↗

Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival.Semantic proximity Read ↗

SPIN1 promotes tumorigenesis by blocking the uL18 (universal large ribosomal subunit protein 18)-MDM2-p53 pathway in human cancerSemantic proximity Read ↗

The ribosomal protein L22 binds the <i>MDM4</i> pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stressSemantic proximity Read ↗

Myeloid Leukemia-Associated Nucleophosmin Mutants Perturb p53-Dependent and Independent Activities of the Arf Tumor Suppressor ProteinSemantic proximity Read ↗

miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination.Semantic proximity Read ↗

Putting a Finger on Growth Surveillance: Insight into MDM2 Zinc Finger-Ribosomal Protein InteractionsSemantic proximity Read ↗

The RNA binding activity of a ribosome biogenesis factor, nucleophosmin/B23, is modulated by phosphorylation with a cell cycle-dependent kinase and by association with its subtype.Semantic proximity Read ↗

Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.