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Article

<scp>GLTSCR</scp>2 is an upstream negative regulator of nucleophosmin in cervical cancer

27 Mar 2015

Abstract excerpt

Nucleophosmin (NPM)/B23, a multifunctional nucleolar phosphoprotein, plays an important role in ribosome biogenesis, cell cycle regulation, apoptosis and cancer pathogenesis. The role of NPM in cells is determined by several factors, including total expression level, oligomerization or phosphorylation status, and subcellular localization. In the nucleolus, NPM participates in rRNA maturation to enhance ribosomal...

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PMID: 25818168
DOI: 10.1111/jcmm.12474

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