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Article

Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex.

Molecular cell - 13 Aug 2010

Dou Hong, Huang Chao, Singh Melissa, Carpenter Phillip B, Yeh Edward T H

Abstract excerpt

The replication protein A complex (RPA) plays a crucial role in DNA replication and damage response. However, it is not known whether this complex is regulated by the SUMOylation pathway. Here, we show that the 70 kDa subunit of RPA (RPA70) associates with a Sentrin/SUMO-specific protease, SENP6,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20705237
DOI: 10.1016/j.molcel.2010.07.021
PMCID: PMC2928994

Genes

SENP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20705237-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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