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Article

CRMP5 interacts with tubulin to inhibit neurite outgrowth, thereby modulating the function of CRMP2.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 11 Aug 2010

Brot Sébastien, Rogemond Véronique, Perrot Valérie, Chounlamountri Naura, Auger Carole, Honnorat Jérôme, Moradi-Améli Mahnaz

Abstract excerpt

Collapsin response mediator proteins (CRMPs) are involved in signaling of axon guidance and neurite outgrowth during neural development and regeneration. Among these, CRMP2 has been identified as an important actor in neuronal polarity and axon outgrowth, these activities being correlated with the reorganization of cytoskeletal proteins. In contrast, the function of CRMP5, expressed during brain development,...

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Source

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Identifiers

PMID: 20702696
DOI: 10.1523/JNEUROSCI.0059-10.2010
PMCID: PMC6634709

Genes

MAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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