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Article

Inhibition of CRMP2 phosphorylation repairs CNS by regulating neurotrophic and inhibitory responses.

Experimental neurology - 1 Mar 2016

Nagai Jun, Owada Kazuki, Kitamura Yoshiteru, Goshima Yoshio, Ohshima Toshio

Abstract excerpt

Central nervous system (CNS) regeneration is restricted by both the lack of neurotrophic responses and the presence of inhibitory factors. As of yet, a common mediator of these two pathways has not been identified. Microtubule dynamics is responsible for several key processes after CNS injuries: intracellular trafficking of receptors for neurotrophic factors, axonal retraction by inhibitory factors, and secondary...

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Identifiers

PMID: 26795088
DOI: 10.1016/j.expneurol.2016.01.015

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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