Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CRMP4 regulates dendritic growth and maturation via the interaction with actin cytoskeleton in cultured hippocampal neurons.

Brain research bulletin - 1 Jun 2016

Cha Caihui, Zhang Jifeng, Ji Zhisheng, Tan Minghui, Li Sumei, Wu Fengming, Chen Keen, Gong Sitang, Guo Guoqing, Lin Hongsheng

Abstract excerpt

CRMP family proteins (CRMPs) are critical for neurite outgrowth and maturation in the developing nervous system. However, the distinct roles of CRMP isoforms remain to be elucidated, especially in dendritic development. Here, we show that CRMP4 is sufficient and necessary for dendritic growth and maturation in cultured hippocampal neurons. Overexpression of CRMP4 promotes and genetic knockdown of CRMP4 inhibits...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin Cytoskeleton
Share to Animals, Newborn

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendrites

Share to Disks Large Homolog 4 Protein

Share to Excitatory Postsynaptic Potentials

Share to Hippocampus

Share to Rats, Sprague-Dawley

Share to RNA, Small Interfering

Source

Identifiers

PMID: 27339813
DOI: 10.1016/j.brainresbull.2016.06.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CRMP4 regulates dendritic growth and maturation via the interaction with actin cytoskeleton in cultured hippocampal neurons.PMID 27339813Read ↗

Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons.Semantic proximity Read ↗

Regulation of dendritic development by BDNF requires activation of CRTC1 by glutamate.Semantic proximity Read ↗

Postsynaptic PDLIM5/Enigma Homolog binds SPAR and causes dendritic spine shrinkage.Semantic proximity Read ↗

SUMOylation of FOXP1 regulates transcriptional repression via CtBP1 to drive dendritic morphogenesis.Semantic proximity Read ↗

Cortactin-binding protein 2 modulates the mobility of cortactin and regulates dendritic spine formation and maintenance.Semantic proximity Read ↗

Neuron-enriched phosphatase and actin regulator 3 (Phactr3)/ nuclear scaffold-associated PP1-inhibiting protein (Scapinin) regulates dendritic morphology via its protein phosphatase 1-binding domain.Semantic proximity Read ↗

A dual shaping mechanism for postsynaptic ephrin-B3 as a receptor that sculpts dendrites and synapses.Semantic proximity Read ↗

CRMP5 interacts with tubulin to inhibit neurite outgrowth, thereby modulating the function of CRMP2.Semantic proximity Read ↗

Interaction of Cupidin/Homer2 with two actin cytoskeletal regulators, Cdc42 small GTPase and Drebrin, in dendritic spines.Semantic proximity Read ↗

Phosphorylation of CRMP2 is involved in proper bifurcation of the apical dendrite of hippocampal CA1 pyramidal neurons.Semantic proximity Read ↗

The Hidden Side of NCAM Family: NCAM2, a Key Cytoskeleton Organization Molecule Regulating Multiple Neural FunctionsSemantic proximity Read ↗

Interaction between telencephalin and ERM family proteins mediates dendritic filopodia formation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.