Article
Uncx regulates proliferation of neural progenitor cells and neuronal survival in the olfactory epithelium.
Molecular and cellular neurosciences - 1 Dec 2010
Sammeta Neeraja, Hardin Debra L, McClintock Timothy S
Abstract excerpt
Uncx (Phd1, Chx4) is a paired homeobox transcription factor gene. It and its probable functional partners, Tle co-repressors, were expressed by neurally-fated basal progenitor cells and olfactory sensory neurons of the olfactory epithelium. Uncx expression was rare in olfactory epithelia of Ascl1(-/-) mice, but common in Neurog1(-/-) mice. In Uncx(-/-) mice olfactory progenitor cell proliferation, progenitor cell...
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