Article
Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis.
Development (Cambridge, England) - 1 Feb 2008
Iulianella Angelo, Sharma Madhulika, Durnin Michael, Vanden Heuvel Greg B, Trainor Paul A
Abstract excerpt
Neurogenesis requires the coordination of neural progenitor proliferation and differentiation with cell-cycle regulation. However, the mechanisms coordinating these distinct cellular activities are poorly understood. Here we demonstrate for the first time that a Cut-like homeodomain transcription factor family member, Cux2 (Cutl2), regulates cell-cycle progression and development of neural progenitors. Cux2...
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