Article
A conserved nuclear receptor, Tailless, is required for efficient proliferation and prolonged maintenance of mushroom body progenitors in the Drosophila brain.
Developmental biology - 1 Feb 2009
Kurusu Mitsuhiko, Maruyama Yasushi, Adachi Yoshitsugu, Okabe Masataka, Suzuki Emiko, Furukubo-Tokunaga Katsuo
Abstract excerpt
The intrinsic neurons of mushroom bodies (MBs), centers of olfactory learning in the Drosophila brain, are generated by a specific set of neuroblasts (Nbs) that are born in the embryonic stage and exhibit uninterrupted proliferation till the end of the pupal stage. Whereas MB provides a unique model to study proliferation of neural progenitors, the underlying mechanism that controls persistent activity of MB-Nbs...
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