Article
Xmrks the spot: life history tradeoffs, sexual selection and the evolutionary ecology of oncogenesis.
Molecular ecology - 1 Aug 2010
Summers Kyle, Crespi Bernard J
Abstract excerpt
In a classic paper, George Williams (1957) argued that alleles promoting reproductive success early in life may be favoured by selection, even if they reduce the lifespan of individuals that bear the allele. A variety of evidence supports the theory that such 'antagonistic pleiotropy' is a major factor contributing to the evolution of senescence (Ljubuncic & Reznick 2009), but examples of specific alleles known...
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