Article
Oncogenesis as a Selective Force: Adaptive Evolution in the Face of a Transmissible Cancer.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Mar 2018
Russell Tracey, Madsen Thomas, Thomas Frédéric, Raven Nynke, Hamede Rodrigo, Ujvari Beata
Abstract excerpt
Similar to parasites, malignant cells exploit the host for energy, resources and protection, thereby impairing host health and fitness. Although cancer is widespread in the animal kingdom, its impact on life history traits and strategies have rarely been documented. Devil facial tumour disease (DFTD), a transmissible cancer, afflicting Tasmanian devils (Sarcophilus harrisii), provides an ideal model system to...
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