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Article

Selection for a dominant oncogene and large male size as a risk factor for melanoma in the Xiphophorus animal model.

Molecular ecology - 1 Aug 2010

Fernandez André A, Bowser Paul R

Abstract excerpt

Adult height is a risk factor in numerous human cancers that involve aberrant receptor tyrosine kinase (RTK) signalling. However, its importance is debated due to conflicting epidemiological studies and the lack of useful in vivo models. In Xiphophorus fishes (Platyfishes/Swordtails), a functional RTK, Xiphophorus melanoma receptor kinase (Xmrk), serves as the dominant oncogene and has been maintained for several...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20618898
DOI: 10.1111/j.1365-294X.2010.04738.x
PMCID: PMC2911510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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