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An Antagonistically Pleiotropic Gene Regulates Vertebrate Growth, Maturity and Aging

2023-05-01

Abstract excerpt

The antagonistic pleiotropy theory of aging predicts functional trade-offs between early-life and late-life fitness. However, empirical evidence for these trade-offs in vertebrates remains scarce, particularly in the context of ecologically relevant life histories. Here, we identify vestigial-like 3 ( vgll3 ), a transcription cofactor previously linked with age at maturity in humans and Atlantic salmon through G...

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Literature Corpus work
a3964641-ff53-5130-a6c4-31167fc56030
DOI
10.1101/2023.05.01.538839
Open publication

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An Antagonistically Pleiotropic Gene Regulates Vertebrate Growth, Maturity and AgingDOI 10.1101/2023.05.01.538839
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