Article
HIV-1 Gag evolution in recently infected human leukocyte antigen-B*57 patients with low-level viremia.
AIDS (London, England) - 24 Sept 2010
Durand Christine M, O'Connell Karen A, Apuzzo Linda G, Langan Susan J, Imteyaz Hejab, Ahonkhai Aima A, Ceccato Christina M, Williams Thomas M, Margolick Joseph B, Blankson Joel N
Abstract excerpt
We studied viral evolution in five human leukocyte antigen (HLA)-B*57 patients recently infected with HIV-1. Escape mutations in HLA-B*57-restricted Gag epitopes were present at study entry in all patients, but were not associated with significant increases in viremia. Conversely, no new escape mutations in HLA-B*57-restricted epitopes or known compensatory mutations were detected in patients who experienced...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
