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Article

A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9.

Kidney international - 1 Oct 2010

Genovese Giulio, Tonna Stephen J, Knob Andrea U, Appel Gerald B, Katz Avi, Bernhardy Andrea J, Needham Alexander W, Lazarus Ross, Pollak Martin R

Abstract excerpt

Genetic variation at the MYH9 locus is linked to the high incidence of focal segmental glomerulosclerosis (FSGS) and non-diabetic end-stage renal disease among African Americans. To further define risk alleles with FSGS we performed a genome-wide association analysis using more than one million single-nucleotide polymorphisms in 56 African-American and 61 European-American patients with biopsy-confirmed FSGS....

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Topics

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Share to Apolipoprotein L1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Glomerulosclerosis, Focal Segmental

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Share to Myosin Heavy Chains

Source

Open in PubMed Open full text

Identifiers

PMID: 20668430
DOI: 10.1038/ki.2010.251
PMCID: PMC3001190

Genes

APOL1
MYH9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9.PMID 20668430Read ↗

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