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Article

Genetic variation in APOL1 and MYH9 genes is associated with chronic kidney disease among Nigerians.

International urology and nephrology - 1 Apr 2013

Tayo Bamidele O, Kramer Holly, Salako Babatunde L, Gottesman Omri, McKenzie Colin A, Ogunniyi Adesola, Bottinger Erwin P, Cooper Richard S

Abstract excerpt

PURPOSE: A region of chromosome 22 which includes APOL1 and MYH9 genes was recently identified as a risk locus for non-diabetic forms of kidney disease, including idiopathic and HIV-associated focal segmental glomerular sclerosis and kidney disease clinically attributed to hypertension among African Americans. The purposes of the current study were, therefore, to examine the frequency of these variants and to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22956460
DOI: 10.1007/s11255-012-0263-4
PMCID: PMC3599169

Genes

APOL1
MYH9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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Genetic variation in APOL1 and MYH9 genes is associated with chronic kidney disease among Nigerians.PMID 22956460Read ↗

Erratum to: Genetic variation in APOL1 and MYH9 genes is associated with chronic kidney disease among NigeriansSemantic proximity Read ↗

High population frequencies of APOL1 risk variants are associated with increased prevalence of non-diabetic chronic kidney disease in the Igbo people from south-eastern Nigeria.Semantic proximity Read ↗

The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans.Semantic proximity Read ↗

The MYH9/APOL1 region and chronic kidney disease in European-Americans.Semantic proximity Read ↗

Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans.Semantic proximity Read ↗

The population genetics of chronic kidney disease: insights from the MYH9-APOL1 locus.Semantic proximity Read ↗

Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene.Semantic proximity Read ↗

APOL1 variants and kidney disease. There is no such thing as a free lunch.Semantic proximity Read ↗

Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD.Semantic proximity Read ↗

Polymorphisms in the non-muscle myosin heavy chain gene (MYH9) are associated with lower glomerular filtration rate in mixed ancestry diabetic subjects from South Africa.Semantic proximity Read ↗

A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9.Semantic proximity Read ↗

Non-diabetic end-stage renal disease in Saudis associated with polymorphism of MYH9 gene but not UMOD gene.Semantic proximity Read ↗

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