Article
Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Apr 2012
Cooke Jessica N, Bostrom Meredith A, Hicks Pamela J, Ng Maggie C Y, Hellwege Jacklyn N, Comeau Mary E, Divers Jasmin, Langefeld Carl D, Freedman Barry I, Bowden Donald W
Abstract excerpt
BACKGROUND: Polymorphisms in the non-muscle myosin IIA gene (MYH9) are associated with focal segmental glomerulosclerosis (FSGS) and non-diabetic end-stage renal disease (ESRD) in African Americans and FSGS in European Americans. We tested for association of single nucleotide polymorphisms (SNPs) in MYH9 with T2DM-ESRD in European Americans; additionally, three APOL1 gene variants were evaluated. METHODS: Fifteen...
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