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Article

Computational approaches for the identification of cancer genes and pathways.

Wiley interdisciplinary reviews. Systems biology and medicine - 1 Jan 2017

Dimitrakopoulos Christos M, Beerenwinkel Niko

Abstract excerpt

High-throughput DNA sequencing techniques enable large-scale measurement of somatic mutations in tumors. Cancer genomics research aims at identifying all cancer-related genes and solid interpretation of their contribution to cancer initiation and development. However, this venture is characterized by various challenges, such as the high number of neutral passenger mutations and the complexity of the biological...

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PMID: 27863091
DOI: 10.1002/wsbm.1364
PMCID: PMC5215607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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