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Article

Oncogenes and tumor suppressor genes: comparative genomics and network perspectives.

BMC genomics - 1 Jan 2015

Zhu Kevin, Liu Qi, Zhou Yubo, Tao Cui, Zhao Zhongming, Sun Jingchun, Xu Hua

Abstract excerpt

BACKGROUND: Defective tumor suppressor genes (TSGs) and hyperactive oncogenes (OCGs) heavily contribute to cell proliferation and apoptosis during cancer development through genetic variations such as somatic mutations and deletions. Moreover, they usually do not perform their cellular functions individually but rather execute jointly. Therefore, a comprehensive comparison of their mutation patterns and network...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26099335
DOI: 10.1186/1471-2164-16-S7-S8
PMCID: PMC4474543

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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