Article
Discovery of co-occurring driver pathways in cancer.
BMC bioinformatics - 9 Aug 2014
Zhang Junhua, Wu Ling-Yun, Zhang Xiang-Sun, Zhang Shihua
Abstract excerpt
BACKGROUND: It has been widely realized that pathways rather than individual genes govern the course of carcinogenesis. Therefore, discovering driver pathways is becoming an important step to understand the molecular mechanisms underlying cancer and design efficient treatments for cancer patients. Previous studies have focused mainly on observation of the alterations in cancer genomes at the individual gene or...
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