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Article

Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea.

PloS one - 22 Jul 2010

Jahan Israt, Pan Ning, Kersigo Jennifer, Fritzsch Bernd

Abstract excerpt

BACKGROUND: At least five bHLH genes regulate cell fate determination and differentiation of sensory neurons, hair cells and supporting cells in the mammalian inner ear. Cross-regulation of Atoh1 and Neurog1 results in hair cell changes in Neurog1 null mice although the nature and mechanism of the cross-regulation has not yet been determined. Neurod1, regulated by both Neurog1 and Atoh1, could be the mediator of...

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Identifiers

PMID: 20661473
DOI: 10.1371/journal.pone.0011661
PMCID: PMC2908541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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