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Article

Correct timing of proliferation and differentiation is necessary for normal inner ear development and auditory hair cell viability.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2013

Kopecky Benjamin J, Jahan Israt, Fritzsch Bernd

Abstract excerpt

BACKGROUND: Hearing restoration through hair cell regeneration will require revealing the dynamic interactions between proliferation and differentiation during development to avoid the limited viability of regenerated hair cells. Pax2-Cre N-Myc conditional knockout (CKO) mice highlighted the need of N-Myc for proper neurosensory development and possible redundancy with L-Myc. The late-onset hair cell death in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23193000
DOI: 10.1002/dvdy.23910
PMCID: PMC3553268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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