Article
Toll-like receptor (TLR)-9 genetics and function in sarcoidosis.
Clinical and experimental immunology - 1 Oct 2010
Veltkamp M, Van Moorsel C H M, Rijkers G T, Ruven H J T, Van Den Bosch J M M, Grutters J C
Abstract excerpt
Sarcoidosis is a systemic disorder characterized by the formation of non-caseating granulomas in variable organs. Toll-like receptor (TLR)-9 is important in the innate immune response against both Mycobacterium tuberculosis and Propionibacterium acnes, candidate causative agents in sarcoidosis. The aim of our study was to investigate possible genetic and functional differences in TLR-9 between patients and...
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