Article
TLR7 Gln11Leu single nucleotide polymorphism in patients with sarcoidosis.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG - 1 Aug 2013
Bordignon M, Bargagli E, Agostini C, Cinetto F, Baldo V, Alaibac M, Rottoli P
Abstract excerpt
Sarcoidosis is a multi-factorial systemic disease with increased activity of the cellular immune components which is responsible of the formation of non-caseating granulomas in involved organs. Recent views on the etiology indicate interactions between inherited susceptibility and environmental or lifestyle factors. Concerning genes that may influence susceptibility to sarcoidosis Toll-like receptors (TLRs) may...
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