Article
Immunogenetics of Disease-Causing Inflammation in Sarcoidosis.
Clinical reviews in allergy & immunology - 1 Aug 2015
Grunewald Johan, Spagnolo Paolo, Wahlström Jan, Eklund Anders
Abstract excerpt
Sarcoidosis is a systemic inflammatory disorder characterised by tissue infiltration by mononuclear phagocytes and lymphocytes with associated non-caseating granuloma formation. Originally described as a disorder of the skin, sarcoidosis can involve any organ with wide-ranging clinical manifestations and disease course. Recent studies have provided new insights into the mechanisms involved in disease...
Topics
- Cytokines
- Erythema Nodosum
- Gene Expression Regulation
- Granuloma
- Histocompatibility Antigens Class II
- Humans
- Inflammation
- Lymphatic Diseases
- Macrophages
- Mycobacterium tuberculosis
- Phenotype