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Article

Toll-like receptor (TLR) 4 polymorphism Asp299Gly is not associated with disease course in Dutch sarcoidosis patients.

Clinical and experimental immunology - 1 Aug 2006

Veltkamp M, Grutters J C, van Moorsel C H M, Ruven H J T, van den Bosch J M M

Abstract excerpt

The aetiology of sarcoidosis, a systemic disorder characterized by the formation of non-caseating granulomas in variable organs, remains enigmatic. Clarification is hampered by heterogeneity in disease phenotypes and course, due partly to the influence of a variety of genetic and environmental factors. Multiple studies have pointed towards bacteria as possible causative agents. Toll-like receptors (TLR) are...

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Identifiers

PMID: 16879239
DOI: 10.1111/j.1365-2249.2006.03127.x
PMCID: PMC1809680

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