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Article

Mutational analysis of the C-terminal FATC domain of Saccharomyces cerevisiae Tra1.

Current genetics - 1 Oct 2010

Hoke Stephen M T, Irina Mutiu A, Genereaux Julie, Kvas Stephanie, Buck Michael, Yu Michael, Gloor Gregory B, Brandl Christopher J

Abstract excerpt

Tra1 is a component of the Saccharomyces cerevisiae SAGA and NuA4 complexes and a member of the PIKK family, which contain a C-terminal phosphatidylinositol 3-kinase-like (PI3K) domain followed by a 35-residue FATC domain. Single residue changes of L3733A and F3744A, within the FATC domain, resulted in transcriptional changes and phenotypes that were similar but not identical to those caused by mutations in the...

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Source

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Identifiers

PMID: 20635087
DOI: 10.1007/s00294-010-0313-3
PMCID: PMC2943577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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