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Article

Role of epigenetics in Rett syndrome.

Epigenomics - 1 Jan 2013

Kubota Takeo, Miyake Kunio, Hirasawa Takae

Abstract excerpt

Rett syndrome (RTT) is an X-linked neurodevelopmental disease caused by MECP2 mutations. The MeCP2 protein was originally thought to function as a transcription repressor by binding to methylated CpG dinucleotides, but is now also thought to be a transcription activator. Recent studies suggest that MeCP2 is not only being expressed in neurons, but also in glial cells, which suggests a new paradigm for...

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Source

Identifiers

PMID: 24059803
DOI: 10.2217/epi.13.54

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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