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Article

Abnormalities in the handling of intracellular bacteria in Crohn's disease.

Journal of clinical gastroenterology - 1 Sept 2010

Lapaquette Pierre, Darfeuille-Michaud Arlette

Abstract excerpt

Ileal lesions in Crohn's disease (CD) patients are colonized by pathogenic adherent-invasive Escherichia coli (AIEC) able to invade and to replicate within intestinal epithelial cells. Recent advances have highlighted the importance of the innate immune system and the critical relationship between the gut flora and the intestinal mucosa. Several combinations of genetic predisposing factors to CD have been...

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Source

Identifiers

PMID: 20616747
DOI: 10.1097/MCG.0b013e3181dd4fa5

Genes

IRGM
NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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