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Article

Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant.

PloS one - 1 Jan 2008

Kuballa Petric, Huett Alan, Rioux John D, Daly Mark J, Xavier Ramnik J

Abstract excerpt

The genetic risk factors predisposing individuals to the development of inflammatory bowel disease are beginning to be deciphered by genome-wide association studies. Surprisingly, these new data point towards a critical role of autophagy in the pathogenesis of Crohn's disease. A single common cod...

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Identifiers

PMID: 18852889
DOI: 10.1371/journal.pone.0003391
PMCID: PMC2566595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18852889-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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