Article
Mycobacteria in Crohn's disease: how innate immune deficiency may result in chronic inflammation.
Expert review of clinical immunology - 1 Jul 2010
Lalande Jean-Daniel, Behr Marcel A
Abstract excerpt
Crohn's disease (CD) is often considered to be an autoimmune condition or, alternatively, an autoinflammatory condition, based on the observation of host-directed inflammatory processes. However, the underlying basis of this deleterious inflammatory response remains elusive. Recent findings from genetic and genomic studies have altered the perspective on the pathogenesis of CD, hinting at defects in innate immune...
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