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Article

ARRDC3 suppresses breast cancer progression by negatively regulating integrin β4

5 Jul 2010

Abstract excerpt

Large-scale genetic analyses of human tumor samples have been used to identify novel oncogenes, tumor suppressors and prognostic factors, but the functions and molecular interactions of many individual genes have not been determined. In this study we examined the cellular effects and molecular mechanism of the arrestin family member, ARRDC3, a gene preferentially lost in a subset of breast cancers. Oncomine data...

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PMID: 20603614
DOI: 10.1038/onc.2010.250

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