Article

Increased expression of REG3A promotes tumorigenic behavior in triple negative breast cancer cells

2024-06-03

Abstract excerpt

<title>Abstract</title><p><bold>Background:</bold>Identifying new targets in triple negative breast cancer (TNBC) remains critical. REG3A (regenerating islet-derived protein 3A), a calcium-dependent lectin protein, was thoroughly investigated for its expression and functions in breast cancer.<bold>Methods:</bold>Bioinformatics and local tissue analyses were employed to identify REG3A expression in breast cancer. G...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a4f02e2a-70a7-51d8-8be5-083175d61c3f
DOI: 10.21203/rs.3.rs-4034162/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Increased expression of REG3A promotes tumorigenic behavior in triple negative breast cancer cellsDOI 10.21203/rs.3.rs-4034162/v1Read

Up-regulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer riskSemantic proximity Read

Reg3A (regenerating family member 3 alpha) acts as a tumor suppressor by targeting DMBT1 (deleted in malignant brain tumors 1) in gastric cancerSemantic proximity Read

STAMBPL1 promotes triple-negative breast cancer angiogenesis by upregulating the transcription of GRHL3/HIF1α/VEGFA via FOXO1Semantic proximity Read

Concomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progressionSemantic proximity Read

Reg3β Deficiency Impairs Pancreatic Tumor Growth by Skewing Macrophage PolarizationSemantic proximity Read

GOLPH3: a novel biomarker that correlates with poor survival and resistance to chemotherapy in breast cancerSemantic proximity Read

GLP-1 Targeting Agents Impair Chemoimmunotherapy Effectiveness in Triple-Negative Breast CancerSemantic proximity Read

GRK6 palmitoylation dictates triple-negative breast cancer metastasis via recruiting the β-Arrestin 2/MAPKs/NF-κB signaling axisSemantic proximity Read

Activation of the S100A7/RAGE Pathway by IGF-1 Contributes to Angiogenesis in Breast CancerSemantic proximity Read

RhoBTB3 Regulates Proliferation and Invasion of Breast Cancer Cells via Col1A1Semantic proximity Read

A Pan-Cancer Analysis of Transcription Factor Forkhead Box O-3: FOXO3Semantic proximity Read

LncRNA-encoded polypeptide ASRPS inhibits triple-negative breast cancer angiogenesisSemantic proximity Read