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EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration

2024-06-28

Abstract excerpt

EPLIN, an actin-binding protein, has been described as both a tumour promoter and tumour suppressor in different cancers. EPLIN isoform(α or β)-specific functions, which remain largely unknown, could explain these opposing roles. We observed distinct EPLIN-isoform localization; EPLINα is recruited to actin in plasma membrane ruffles and endosomes, while EPLINβ resides on actin stress fibers. We identified two EPLI...

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Identifiers and source

Literature Corpus work
033c0c88-b105-5793-b363-1d2ff8d4b4dc
DOI
10.1101/2024.06.27.600789
Open publication

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EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migrationDOI 10.1101/2024.06.27.600789
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