Article
Bivariate genetic association of KIAA1797 with heart rate in American Indians: the Strong Heart Family Study.
Human molecular genetics - 15 Sept 2010
Melton Phillip E, Rutherford Sue, Voruganti Venkata Saroja, Göring Harald H H, Laston Sandra, Haack Karin, Comuzzie Anthony G, Dyer Thomas D, Johnson Matthew P, Kent Jack W, Curran Joanne E, Moses Eric K, Blangero John, Barac Ana, Lee Elisa T, Best Lyle G, Fabsitz Richard R, Devereux Richard B, Okin Peter M, Bella Jonathan N, Broeckel Uli, Howard Barbara V, MacCluer Jean W, Cole Shelley A, Almasy Laura
Abstract excerpt
Heart rate (HR) has been identified as a risk factor for cardiovascular disease (CVD), yet little is known regarding genetic factors influencing this phenotype. Previous research in American Indians (AIs) from the Strong Heart Family Study (SHFS) identified a significant quantitative trait locus (QTL) for HR on chromosome 9p21. Genetic association on HR was conducted in the SHFS. HR was measured from...
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