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A quantitative trait loci-specific gene-by-sex interaction on systolic blood pressure among American Indians: the Strong Heart Family Study.

Hypertension (Dallas, Tex. : 1979) - 1 Aug 2006

Franceschini Nora, MacCluer Jean W, Göring Harald H H, Cole Shelley A, Rose Kathryn M, Almasy Laura, Diego Vincent, Laston Sandra, Lee Elisa T, Howard Barbara V, Best Lyle G, Fabsitz Richard R, Roman Mary J, North Kari E

Abstract excerpt

Age-adjusted systolic blood pressure is higher in males than females. Genetic factors may account for this sex-specific variation. To localize sex-specific quantitative trait loci (QTL) influencing blood pressure, we conducted a genome scan of systolic blood pressure, in males and females, separately and combined, and tested for aggregate and QTL-specific genotype-by-sex interaction in American Indian...

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PMID: 16818806
DOI: 10.1161/01.HYP.0000231651.91523.7e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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