Article
Mapping of a blood pressure QTL on chromosome 17 in American Indians of the strong heart family study.
BMC cardiovascular disorders - 11 Nov 2014
Franceschini Nora, Tao Ran, Liu Lan, Rutherford Sue, Haack Karin, Almasy Laura, Göring Harald Hh, Laston Sandra, Lee Elisa T, Best Lyle G, Fabsitz Richard, Cole Shelley A, North Kari E
Abstract excerpt
BACKGROUND: Blood pressure (BP) is a complex trait, with a heritability of 30 to 40%. Several genome wide associated BP loci explain only a small fraction of the phenotypic variation. Family studies can provide an important tool for gene discovery by utilizing trait and genetic transmission information among relative-pairs. We have previously described a quantitative trait locus at chromosome 17q25.3 influencing...
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