Article
Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study.
BMC medical genetics - 19 Sept 2007
Newton-Cheh Christopher, Guo Chao-Yu, Wang Thomas J, O'donnell Christopher J, Levy Daniel, Larson Martin G
Abstract excerpt
BACKGROUND: Heritable electrocardiographic (ECG) and heart rate variability (HRV) measures, reflecting pacemaking, conduction, repolarization and autonomic function in the heart have been associated with risks for cardiac arrhythmias. Whereas several rare monogenic conditions with extreme phenotypes have been noted, few common genetic factors contributing to interindividual variability in ECG and HRV measures...
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